Evaluation of prognostic factors and comparison of systemic treatment modalities in patients with recurrent or metastatic endometrial carcinoma


Karagol H., Saip P., Uygun K., Kucucuk S., Aydiner A., Topuz E.

MEDICAL ONCOLOGY, vol.23, no.4, pp.543-548, 2006 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 23 Issue: 4
  • Publication Date: 2006
  • Doi Number: 10.1385/mo:23:4:543
  • Journal Name: MEDICAL ONCOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.543-548
  • Keywords: endometrial carcinoma, metastasis or recurrence, prognostic factors, systemic treatment, GYNECOLOGIC-ONCOLOGY-GROUP, PHASE-II TRIAL, CANCER, CHEMOTHERAPY
  • Kocaeli University Affiliated: Yes

Abstract

Background: Prognostic factors related to survival in patients with inoperable metastatic or recurrent endometrial carcinoma (MREC) have remained unclear due to lack of clinical trials.The management of these patients is also controversial.This study was performed to compare the efficacy and toxicity profiles of two different systemic therapies (chemotherapy vs hormonal therapy) given for the treatment of patients with MREC and to identify the impact of various prognostic factors on the survival.