Serum hepcidin and growth differentiation factor-15 (GDF-15) levels in polycythemia vera and essential thrombocythemia

TARKUN P. , MEHTAP Ö. , Atesoglu E. B. , GEDÜK A. , Musul M. M. , Hacihanefioglu A.

EUROPEAN JOURNAL OF HAEMATOLOGY, cilt.91, sa.3, ss.228-235, 2013 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 91 Konu: 3
  • Basım Tarihi: 2013
  • Doi Numarası: 10.1111/ejh.12150
  • Dergi Adı: EUROPEAN JOURNAL OF HAEMATOLOGY
  • Sayfa Sayıları: ss.228-235

Özet

Objectives Hepcidin plays a regulatory role in systemic iron homeostasis. GDF-15 has been found to be expressed from matured erythroblasts and very high levels of GDF-15 suppresses hepcidin secretion. In this study, we evaluated hepcidin and GDF-15 levels in polycythemia vera (PV) and essential thrombocythemia (ET).