Rapamycin Improves Vascular Remodelling in a Controlled Rat Model of Monocrotaline-Induced Pulmonary Hypertension

Sengul A., Vural C., Arkan S., Ozer C., Bayrak B. Y., Tas A., ...Daha Fazla

WEST INDIAN MEDICAL JOURNAL, cilt.69, sa.9, ss.638-644, 2023 (SCI-Expanded, Scopus) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 69 Sayı: 9
  • Basım Tarihi: 2023
  • Doi Numarası: 10.7727/wimj.2015.222
  • Dergi Adı: WEST INDIAN MEDICAL JOURNAL
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, CAB Abstracts, CINAHL, EMBASE, Veterinary Science Database
  • Sayfa Sayıları: ss.638-644
  • Anahtar Kelimeler: Life expectancy, pulmonary hypertension, rapamycin, vascular remodelling, ARTERIAL-HYPERTENSION, CELL PROLIFERATION, MTOR, EVEROLIMUS, EXPRESSION, INHIBITORS, SIROLIMUS, FIBROSIS, THERAPY, TARGET
  • Kocaeli Üniversitesi Adresli: Evet

Özet

Background: Pulmonary arterial hypertension (PAH) is a serious disease characterized by the progressive elevation of the pulmonary arterial resistance, leading to the right ventricular failure and death.