Protective Effects of Pentoxifylline and Nimodipine on Acoustic Trauma in Guinea Pig Cochlea

Kansu L., ÖZKARAKAŞ H., EFENDİ H., Okar I.

OTOLOGY & NEUROTOLOGY, vol.32, no.6, pp.919-925, 2011 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 32 Issue: 6
  • Publication Date: 2011
  • Doi Number: 10.1097/mao.0b013e3182267e06
  • Journal Name: OTOLOGY & NEUROTOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.919-925
  • Keywords: Acoustic trauma, Cochlea, Nimodipine, Pentoxifylline, INDUCED HEARING-LOSS, INNER-EAR DISEASE, BLOOD-FLOW, CALCIUM-CHANNEL, MOUSE COCHLEA, INJURY, OVERSTIMULATION, POTENTIALS, ANTAGONIST, HYPOXIA
  • Kocaeli University Affiliated: Yes

Abstract

Objective: To examine the protective effects of the vasodilator and hemorheologically active drug pentoxifylline and the calcium channel blocker nimodipine on the cochlea after acoustic overexposure in guinea pigs.