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Pinarbasi A. S., DURSUN İ., GÖKCE İ., ÇOMAK E., Saygili S., BAYRAM M. T., ...More
PEDIATRIC NEPHROLOGY, vol.36, no.5, pp.1195-1205, 2021 (SCI-Expanded)
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Publication Type:
Article / Article
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Volume:
36
Issue:
5
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Publication Date:
2021
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Doi Number:
10.1007/s00467-020-04799-7
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Journal Name:
PEDIATRIC NEPHROLOGY
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Journal Indexes:
Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, CAB Abstracts, CINAHL, EMBASE, MEDLINE, Veterinary Science Database
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Page Numbers:
pp.1195-1205
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Keywords:
Complement, CKD stage 5, Children, C3 glomerulopathy, Predictors, DENSE DEPOSIT DISEASE, MYCOPHENOLATE-MOFETIL, MEMBRANOPROLIFERATIVE GLOMERULONEPHRITIS, POSTINFECTIOUS GLOMERULONEPHRITIS, ECULIZUMAB, EXPERIENCE
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Kocaeli University Affiliated:
No
Abstract
Background C3 glomerulopathy (C3G) is characterized by heterogeneous clinical presentation, outcome, and predominant C3 accumulation in glomeruli without significant IgG. There is scarce outcome data regarding childhood C3G. We describe clinical and pathological features, treatment and outcomes, and risk factors for progression to chronic kidney disease stage 5 (CKD5) in the largest pediatric series with biopsy-proven C3G.