The effect of generalized seizure activity on ischemia-induced cardiac arrhythmias and myocardial injury with histopathological evaluation in anesthetized rats

Gonca E., Barut F., ŞAHİN D.

TURKISH JOURNAL OF MEDICAL SCIENCES, vol.48, no.6, pp.1293-1301, 2018 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 48 Issue: 6
  • Publication Date: 2018
  • Doi Number: 10.3906/sag-1807-99
  • Journal Name: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.1293-1301
  • Keywords: Epilepsy, pentylentetrazole, ventricular arrhythmias, myocardial injury, rat, SUDDEN UNEXPECTED DEATH, EPILEPSY, INFARCTION, RISK
  • Kocaeli University Affiliated: Yes

Abstract

Background/aim: Epileptic seizure leads to sudden unexpected death in epilepsy (SUDEP) among affected patients. The causes of SUDEP are still unclear. The aim of this study was to research the effect of epilepsy on myocardial injury and arrhythmias during experimentally induced acute myocardial ischemia.