Inflammation in Benign Prostate Tissue and Prostate Cancer in the Finasteride Arm of the Prostate Cancer Prevention Trial

Murtola, Teemu; GÜREL, BORA; Umbehr, Martin; Lucia, M.; Thompson, Ian; Goodman, Phyllis; Kristal, Alan; Parnes, Howard; Lippman, Scott; Sutcliffe, Siobhan; Peskoe, Sarah; Barber, John; Drake, Charles; Nelson, William; De Marzo, Angelo; Platz, Elizabeth

doi:10.1158/1055-9965.epi-15-0987

Inflammation in Benign Prostate Tissue and Prostate Cancer in the Finasteride Arm of the Prostate Cancer Prevention Trial

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Murtola T. J., GÜREL B., Umbehr M., Lucia M. S., Thompson I. M., Goodman P. J., ...More

CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION, vol.25, no.3, pp.463-469, 2016 (SCI-Expanded)

Publication Type: Article / Article
Volume: 25 Issue: 3
Publication Date: 2016
Doi Number: 10.1158/1055-9965.epi-15-0987
Journal Name: CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.463-469
Kocaeli University Affiliated: Yes

Abstract

Background: A previous analysis of the placebo arm of the Prostate Cancer Prevention Trial (PCPT) reported 82% overall prevalence of intraprostatic inflammation and identified a link between inflammation and higher-grade prostate cancer and serum PSA. Here, we studied these associations in the PCPT finasteride arm.