Imprint cytology in the diagnosis of <i>Helicobacter pylori</i> -: Does imprinting damage the biopsy specimen?

Cubukcu A., Gonullu N., Ercin C., Alponat A., Kaur A., Canturk Z., ...Daha Fazla

ACTA CYTOLOGICA, sa.2, ss.124-127, 2000 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Basım Tarihi: 2000
  • Doi Numarası: 10.1159/000326348
  • Dergi Adı: ACTA CYTOLOGICA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.124-127
  • Kocaeli Üniversitesi Adresli: Evet

Özet

OBJECTIVE: To investigate the efficacy of imprint cytology in the diagnosis of Helicobacter pylori infection and whether it damages the biopsy specimen for subsequent histologic examination. STUDY DESIGN: Two antral biopsies were taken from 76 patients with dyspeptic symptoms undergoing upper gastrointestinal endoscopy. Imprint cytology was made form the first specimen. This specimen was fixed in 10% formalin adn sent for histopathologic examination. The second specimen was directly fixed in 10% formalin for routine histopathologic examination without being used for an imprint. The imprint smears were examined bt cytopathologists. The biopsy specimens were examined by pathologists who did not know which specimens were used for the imprints. RESULTS: H pylori was seen in smears from 55 (72%) patients and in both biopsy specimens from the same patients. The pathologists could not recognize the biopsy specimens from which the imprints were made. Concordance between imprint cytology adn histopathology was 100%. CONCLUSION: Imprint cytology is a suitable test for H pylori diagnosis, and imprints do not adversely affect the quality of the biopsy specimen.