Treatment with chitin microparticles is protective against lung histopathology in a murine asthma model

Ozdemir, C.; Yazi, D.; Aydogan, METİN; Akkoc, T.; Bahceciler, N.; Strong, P.; Barlan, I.

doi:10.1111/j.1365-2222.2006.02515.x

Treatment with chitin microparticles is protective against lung histopathology in a murine asthma model

Atıf İçin Kopyala

Ozdemir C., Yazi D., Aydogan M., Akkoc T., Bahceciler N. N., Strong P., ...Daha Fazla

CLINICAL AND EXPERIMENTAL ALLERGY, cilt.36, sa.7, ss.960-968, 2006 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 36 Sayı: 7
Basım Tarihi: 2006
Doi Numarası: 10.1111/j.1365-2222.2006.02515.x
Dergi Adı: CLINICAL AND EXPERIMENTAL ALLERGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.960-968
Anahtar Kelimeler: airway histopathology, asthma, BALB/c, chitin microparticles, ACIDIC MAMMALIAN CHITINASE, HEAT-KILLED LISTERIA, T-CELL CYTOKINES, CPG OLIGODEOXYNUCLEOTIDES, ATOPIC ASTHMA, INFLAMMATION, MODULATION, RESPONSES, ADJUVANT, IMMUNITY
Kocaeli Üniversitesi Adresli: Evet

Özet

Chitin, a natural polysaccharide extracted from shrimp, is a potent T and B cell adjuvant when delivered in the form of chitin microparticles and can shift a polarized T-helper type 2 (Th2) immune response towards a Th1 response.