Akademik Veri Yönetim Sistemi
Acta Medica Nicomedia, cilt.7, sa.3, ss.301-307, 2024 (Hakemli Dergi)
Objective: Inflammatory bowel disease patients are prone to be anemic at
diagnosis and follow-up. As it is a common extra-intestinal
manifestation, its early identification and treatment are essential. We
aimed to evaluate the frequency, types, and predictors of anemia and its
treatment in pediatric inflammatory bowel disease patients.
Methods: The electronic records of pediatric IBD patients who attended
our outpatient clinics between 1 April 2018 and 01 May 2019 were
retrospectively evaluated. Patients who had the results of hemoglobin,
hematocrit, mean corpuscular volume, iron indices, vitamin B12 level,
folic acid level, reticulocyte count, C-reactive protein, and
erythrocyte sedimentation rate at least once on a single day were
included in the study. Laboratory results associated with anemia and
disease activity index scores at three- and six-months follow-ups were
recorded. Anemia was diagnosed according to WHO criteria in childhood.
Anemia, risk factors, and management of anemia were determined.
Results: Forty patients were included in the study. At first evaluation,
anemia was observed in 38.1% of Crohn’s disease patients and 57.9% of
ulcerative colitis patients. Iron deficiency anemia was the main type of
anemia in both groups. The rate of anemia decreased at follow-up. Out
of 40 patients, 21 had treatment at the initial evaluation. Active
disease was the only predictor of iron deficiency anemia.
Conclusion: Anemia was common in pediatric inflammatory bowel disease
patients, ranging between 25-47.5% during the 6-month follow-up in our
study. Iron deficiency anemia was the main type of anemia. Having active
disease was the only risk factor for anemia. The treatment of anemia
and iron deficiency without anemia should be kept in mind in parallel
with anti-inflammatory treatment.