IL-22-secreting Th22 and IFN-gamma-secreting Th17 cells in Behcet's disease


Cetin E. A. , Cosan F., ÇEFLE A. , Deniz G.

MODERN RHEUMATOLOGY, cilt.24, ss.802-807, 2014 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 24 Konu: 5
  • Basım Tarihi: 2014
  • Doi Numarası: 10.3109/14397595.2013.879414
  • Dergi Adı: MODERN RHEUMATOLOGY
  • Sayfa Sayısı: ss.802-807

Özet

Objective. Behcet's disease (BD) is a systemic inflammatory disease with unknown etiology. Studies have shown that some T helper (Th) 1-associated cytokines have role in the inflammation of BD. The CD4(+) Th cells can be differentiated into Th1, Th2, Th17 and Th22 secrete different cytokines to regulate immune system. In this study, cytokine secretion of Th subsets in BD was investigated.