IL-22-secreting Th22 and IFN-gamma-secreting Th17 cells in Behcet's disease

Cetin E. A., Cosan F., ÇEFLE A., Deniz G.

MODERN RHEUMATOLOGY, vol.24, no.5, pp.802-807, 2014 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 24 Issue: 5
  • Publication Date: 2014
  • Doi Number: 10.3109/14397595.2013.879414
  • Journal Name: MODERN RHEUMATOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.802-807
  • Kocaeli University Affiliated: Yes

Abstract

Objective. Behcet's disease (BD) is a systemic inflammatory disease with unknown etiology. Studies have shown that some T helper (Th) 1-associated cytokines have role in the inflammation of BD. The CD4(+) Th cells can be differentiated into Th1, Th2, Th17 and Th22 secrete different cytokines to regulate immune system. In this study, cytokine secretion of Th subsets in BD was investigated.