Heavy metals released into the environment continue to receive attention over with advances of technology, but with variations in concentration. Heavy metals released into the environment in various concentrations continue to receive attention, fostered by advances in technology. Lead, one of the best-known heavy metals, can be found at high levels in industrial wastewater, is nonbiodegradable, and is a neurotoxic metal. To remove Pb(II) ions from aqueous solutions, the adsorption process of Pb(II) ions was optimized by using response surface methodology (RSM). The effects of initial pH, initial concentration of lead, and temperature on the adsorption efficiency (E, %) were investigated. pH was the most significant factor that affected the removal of lead. Central composite design (CCD) can be successfully applied to the removal of Pb(II) ions from aqueous solutions.