Akademik Veri Yönetim Sistemi
Journal of the Faculty of Engineering and Architecture of Gazi University, cilt.40, sa.3, ss.1903-1919, 2025 (SCI-Expanded)
In this study, Poly (lactic acid) (PLA) matrix was mixed with Poly(butylene succinate) (PBS) in certain ratios (3%, 5%, 7%, and 10% by weight) to improve its mechanical properties, and nanofibers were produced by single-feed electrospinning method. The plasticizing effect of PBS on PLA was investigated by Scanning Electron Microscope (SEM), Fourier Transform Infrared (FTIR), Differential Scanning Calorimetry (DSC), mechanical analysis, and contact angle tests. The optimum mixing ratio of PLA with PBS was determined as 7%. The % elongation of PLA-7PBS nanofiber (15.05%) increased approximately 3 times compared to that of pure PLA (5.46%). Moreover, PLA-7PBS nanofiber was obtained as the material closest to the superhydrophobic character with a contact angle value of 147°. Then, hollow nanofiber was produced using the double-feed electrospinning method from the optimum PLA/PBS mixture ratio. The hollow of nanofiber was proven by SEM, FTIR, and DSC analyses. While the tensile strength of PLA-7PBS nanofiber was 0.31 MPa, that of PLA-7PBS-hollow nanofiber increased to 0.61 MPa. The cytotoxicity of PLA-7PBS-hollow nanofiber against fibroblast cell line was examined at 24th and 48th hours. Additionally, liquid absorption capacity and drying time tests were performed instead of PLA-7PBS-hollow nanolife contact angle testing. The highly hydrophobic PLA-7PBS structure had a high liquid absorption capacity of 611.90% when hollow. PLA-7PBS-hollow nanofiber exhibited 122% and 118% fibroblast cell viability at 24 and 48 hours, respectively. The biocompatible and biodegradable PLA-7PBS-hollow nanomaterial has been presented as a potential wound-dressing candidate.