Intraoperative mitomycin C in the treatment of pterygium

Yanyali A., Talu H., Alp B., Karabas L., Manav G., Caglar Y.

CORNEA, cilt.19, sa.4, ss.471-473, 2000 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 19 Sayı: 4
  • Basım Tarihi: 2000
  • Doi Numarası: 10.1097/00003226-200007000-00013
  • Dergi Adı: CORNEA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.471-473
  • Kocaeli Üniversitesi Adresli: Evet

Özet

Purpose. To evaluate the effectiveness of intraoperative mitomycin C in preventing the recurrence of primary pterygium. Methods. In this prospective, randomized study, 38 eyes of 35 patients with primary pterygium were evaluated. In 19 eyes, the "bare sclera technique" combined with intraoperative application of 0.2 mg/mL (0.02%) mitomycin C for five minutes was performed (mitomycin C treated group). The other 19 eyes-taken as control group-underwent surgical excision alone. Statistics were analyzed using the Mann-Whitney U test and the Fischer's exact test. Results. Patients were 20-38 years of age. The mean age was 25.29 +/- 5.08 in the mitomycin C treated group and 25.00 +/- 5.14 in the control group. During the mean follow-up of 17.04 months (range, 12-36 months; SD = 5.89), 4 recurrences (21%) were observed in the mitomycin C: treated group and 11 (57.8%) in the control group. The difference between the two groups was significant(p = 0.045). No postoperative complication was encountered in both groups except for recurrences. Conclusion. Intraoperative mitomycin C was found to be effective in preventing the recurrence of primary pterygium.