Akademik Veri Yönetim Sistemi
TURKDERM-TURKISH ARCHIVES OF DERMATOLOGY AND VENEROLOGY, cilt.55, sa.3, ss.140-142, 2021 (ESCI)
Dermatofibromas are benign tumors caused by fibroblasts and histiocytes, which are quite common in middle-aged adults. It is characterized by hard, single or multiple, papule, plaque or nodul-shaped lesions that are localized to the lower extremity. Many clinical and pathological variants of dermatofibroma have been identified. One of these variants is atrophic dermatofibroma. Atrophic dermatofibroma is generally seen in middle-aged women as lesions that collapse inward, showing placement on the upper part of the body and arms. It can be confused with morphea, atrophoderma, neurofibroma, localized lipoatrophy, healing panniculitis lesions, anetoderma, steroid atrophy, and basal cell carcinoma. The definitive diagnosis is made by histopathological examination as well as clinical findings. Positive immunohistochemical staining for factor XIIIa, as well as a negative reaction for CD34, support a diagnosis of dermatofibroma. A 38-year-old woman diagnosed with atrophic dermatofibroma is presented here.