The effects of chronic treatment with a calcium channel antagonist on two types of generalized epilepsies in rats

van Luijtelaar E., Ates N., van der Staay F.

Pharmacology, Biochemistry and Behavior, cilt.48, sa.3, ss.575-579, 1994 (SCI-Expanded) identifier identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 48 Sayı: 3
  • Basım Tarihi: 1994
  • Doi Numarası: 10.1016/0091-3057(94)90316-6
  • Dergi Adı: Pharmacology, Biochemistry and Behavior
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.575-579
  • Anahtar Kelimeler: NIMODIPINE, CALCIUM ANTAGONIST, PENTYLENETETRAZOL-INDUCED SEIZURES, ABSENCE EPILEPSY, SPIKE-WAVE DISCHARGES, GENETIC EPILEPSY MODEL, CHRONIC ADMINISTRATION, WISTAR RATS, AGING, SPIKE-WAVE DISCHARGES, ABSENCE EPILEPSY, INDUCED SEIZURES, ANTICONVULSANT PROPERTIES, NEURONS, SUPPRESSION, NIMODIPINE, PAROXYSMS, PATTERNS, BLOCKERS
  • Kocaeli Üniversitesi Adresli: Evet

Özet

We study the most general Multi-Higgs-Doublet Model (MHDM) with Natural Flavor Conservation (NFC). The couplings of a charged scalar $H_i^{\pm}$ to up quarks, down quarks and charged leptons depend on three new complex parameters, $X_i$, $Y_i$ and $Z_i$, respectively. We prove relations among these parameters. We carry out a comprehensive analysis of phenomenological constraints on the couplings of the lightest charged scalar: $X$, $Y$ and $Z$. We find that the general MHDM may differ significantly from its minimal version, the Two-Higgs-Doublet Model (2HDM).