Oxidant and antioxidant levels in preterm newborns with idiopathic hyperbilirubinaemia

Turgut, M; Basaran, O; Cekmen, M; Karatas, F; Kurt, A; Aygun, AD

doi:10.1111/j.1440-1754.2004.00489.x

Oxidant and antioxidant levels in preterm newborns with idiopathic hyperbilirubinaemia

Atıf İçin Kopyala

Turgut M., Basaran O., Cekmen M., Karatas F., Kurt A., Aygun A.

JOURNAL OF PAEDIATRICS AND CHILD HEALTH, cilt.40, sa.11, ss.633-637, 2004 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 40 Sayı: 11
Basım Tarihi: 2004
Doi Numarası: 10.1111/j.1440-1754.2004.00489.x
Dergi Adı: JOURNAL OF PAEDIATRICS AND CHILD HEALTH
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.633-637
Kocaeli Üniversitesi Adresli: Hayır

Özet

Objectives: Newborns, particulary preterm infants, have limited antioxidant protective capacity. The organism's defence system against reactive oxygen species including vitamins A, E and C, trace element selenium (Se) and enzymes, such as catalase (CAT), superoxide dismutase (SOD), and glutathione peroxidase (GSH-Px) are essential components of the antioxidant system against the oxidative injury to the cellular membranes of erythrocytes. In this study, our aim was to compare the oxidant nitric oxide (total plasma nitrite level as an indicator of nitric oxide (NO)), antioxidant vitamins and selenium and erythrocyte antioxidant enzymes in premature babies with hyperbilirubinaemia with healthy preterms.