Multivessel variant angina after a radical nephrectomy operation


URAL E., KILIÇ T., KAHRAMAN G., DİLLİOĞLUGİL Ö., Ural D., Komsuoglux B.

CANADIAN JOURNAL OF CARDIOLOGY, cilt.24, sa.6, 2008 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Editöre Mektup
  • Cilt numarası: 24 Sayı: 6
  • Basım Tarihi: 2008
  • Dergi Adı: CANADIAN JOURNAL OF CARDIOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Kocaeli Üniversitesi Adresli: Evet

Özet

A case of multivessel variant angina after an open radical nephrectomy operation (RNO) is presented. A 52-year-old man was admitted to the coronary care unit with recurrent chest pain and dynamic ST-T wave changes on electrocardiogram early after an RNO. The first diagnosis of the clinical condition was non-ST segment elevation acute coronary syndrome. However, recurrent angina with ST segment elevation occurred after the standard medical therapy, which included beta-blockers. Emergency coronary angiography showed diffuse and multiple narrowing of all the three major coronary arteries during the chest pain, which was relieved by intracoronary nitroglycerine injection. Variant angina was suspected, and beta-blocker therapy was replaced with calcium channel blocker treatment. No angina attacks were observed during the clinical follow-up. Although a direct relationship between the type of surgery and variant angina was not established, coronary vasospasm after an RNO should be kept in mind, especially in the differential diagnosis of a patient with recurrent angina and dynamic ST-T changes on electrocardiogram. Although beta-blocker therapy is a first-line treatment for all acute coronary syndromes, it can be harmful in patients with variant angina and should be stopped immediately after verification of diagnosis.