Increased frequency of MEFV gene mutations in patients with primary dysmenorrhea

ERTEN S., ALTUNOĞLU A., Keskin H. L. , Ceylan G. G. , Yazici A. , Dalgaci A. F. , ...More

MODERN RHEUMATOLOGY, vol.23, no.5, pp.959-962, 2013 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 23 Issue: 5
  • Publication Date: 2013
  • Doi Number: 10.1007/s10165-012-0779-6
  • Title of Journal : MODERN RHEUMATOLOGY
  • Page Numbers: pp.959-962


Familial Mediterranean fever (FMF) is an autoinflammatory disease characterized by recurrent attacks of fever and polyserositis and an autosomal recessive inheritance mode. Up to 15 % of FMF patients are reported to experience perimenstrual attacks. Primary dysmenorrhea could be an incomplete abdominal attack, or patients with dysmenorrhea may have increased frequency of MEFV gene mutation carriage. Therefore, we aimed to evaluate the frequency of MEFV gene mutations in patients with dysmenorrhea.