Anxiolytic-Like and Antidepressant-Like Effects of Resveratrol in Streptozotocin-Induced Diabetic Rats

Demirtaş Şahin T., Göçmez S., Eraldemir F., Utkan T.

NOROPSIKIYATRI ARSIVI-ARCHIVES OF NEUROPSYCHIATRY, vol.56, pp.144-149, 2019 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 56
  • Publication Date: 2019
  • Doi Number: 10.29399/npa.23176
  • Journal Name: NOROPSIKIYATRI ARSIVI-ARCHIVES OF NEUROPSYCHIATRY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.144-149
  • Keywords: Diabetes, depression, anxiety, resveratrol, QUALITY-OF-LIFE, OXIDATIVE STRESS, TRANS-RESVERATROL, DEPRESSION, ANXIETY, MODEL, ANTIOXIDANT, HIPPOCAMPUS
  • Kocaeli University Affiliated: Yes

Abstract

Introduction: Diabetes is associated with anxiety and depression. Resveratrol. one of the most potent natural polyphenols with antioxidant properties, has been demonstrated to have benefits against diabetes. In the current study, we investigated the effects of resveratrol on depression and anxiety-like behaviors in diabetic rats.