Three Different Co-existing α-Thalassemia Mutations and Sickle Cell Disease in a Pregnant Woman

RAHIM F., Hamid F., Galedari H., Khamisipour G., Keikhaei B., Jaseb K., ...More

LABMEDICINE, vol.44, no.1, 2013 (SCI-Expanded, Scopus) identifier

  • Publication Type: Article / Editorial Material
  • Volume: 44 Issue: 1
  • Publication Date: 2013
  • Doi Number: 10.1309/lmkqevyzfo7mv6rz
  • Journal Name: LABMEDICINE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Kocaeli University Affiliated: No

Abstract

Thalassemia is the most frequent single-gene defect and overwhelmingly effects prenatal patients in Iran; the condition is caused by a diverse range of mutations. We discuss an extremely rare combination of alpha-globin gene disease and sickle cell trait. This combination may explain a mild form of thalassemia that presents with moderate anemia.