Three Different Co-existing α-Thalassemia Mutations and Sickle Cell Disease in a Pregnant Woman

RAHIM F., Hamid F., Galedari H., Khamisipour G., Keikhaei B., Jaseb K., ...Daha Fazla

LABMEDICINE, cilt.44, sa.1, 2013 (SCI-Expanded, Scopus) identifier

  • Yayın Türü: Makale / Editöre Mektup
  • Cilt numarası: 44 Sayı: 1
  • Basım Tarihi: 2013
  • Doi Numarası: 10.1309/lmkqevyzfo7mv6rz
  • Dergi Adı: LABMEDICINE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Kocaeli Üniversitesi Adresli: Hayır

Özet

Thalassemia is the most frequent single-gene defect and overwhelmingly effects prenatal patients in Iran; the condition is caused by a diverse range of mutations. We discuss an extremely rare combination of alpha-globin gene disease and sickle cell trait. This combination may explain a mild form of thalassemia that presents with moderate anemia.