The Association Between Gene Polymorphisms and Leukocytosis with Thrombotic Complications in Patients with Essential Thrombocythemia and Polycythemia Vera

MEHTAP Ö., Atesoglu E. B., TARKUN P., GONULLU E., KESKİ H., Topcu Y., ...More

TURKISH JOURNAL OF HEMATOLOGY, vol.29, no.2, pp.162-169, 2012 (SCI-Expanded, Scopus, TRDizin) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 29 Issue: 2
  • Publication Date: 2012
  • Doi Number: 10.5505/tjh.2012.03780
  • Journal Name: TURKISH JOURNAL OF HEMATOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.162-169
  • Keywords: PAI-1 4G/5G, ACE I/D, Polycythemia vera, Essential thrombocythemia, Thrombosis, Leukocytosis, ANGIOTENSIN-CONVERTING ENZYME, ACTIVATOR INHIBITOR-1 PAI-1, 4G/5G POLYMORPHISM, RISK-FACTOR, INSERTION/DELETION POLYMORPHISM, VENOUS THROMBOSIS, MYELOPROLIFERATIVE DISORDERS, DELETION POLYMORPHISM, 4G/4G GENOTYPE, ACE GENE
  • Kocaeli University Affiliated: Yes

Abstract

Objective: Vascular events are a common complication in patients with polycythemia vera (PV) and essential thrombocythemia (ET). This study aimed to analyze the association between PAI-1 4G/5G and ACE I/D gene polymorphisms, and leukocytosis with thrombosis in patients with PV and ET.