The Association Between Gene Polymorphisms and Leukocytosis with Thrombotic Complications in Patients with Essential Thrombocythemia and Polycythemia Vera

MEHTAP Ö., Atesoglu E. B., TARKUN P., GONULLU E., KESKİ H., Topcu Y., ...Daha Fazla

TURKISH JOURNAL OF HEMATOLOGY, cilt.29, sa.2, ss.162-169, 2012 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 29 Sayı: 2
  • Basım Tarihi: 2012
  • Doi Numarası: 10.5505/tjh.2012.03780
  • Dergi Adı: TURKISH JOURNAL OF HEMATOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.162-169
  • Anahtar Kelimeler: PAI-1 4G/5G, ACE I/D, Polycythemia vera, Essential thrombocythemia, Thrombosis, Leukocytosis, ANGIOTENSIN-CONVERTING ENZYME, ACTIVATOR INHIBITOR-1 PAI-1, 4G/5G POLYMORPHISM, RISK-FACTOR, INSERTION/DELETION POLYMORPHISM, VENOUS THROMBOSIS, MYELOPROLIFERATIVE DISORDERS, DELETION POLYMORPHISM, 4G/4G GENOTYPE, ACE GENE
  • Kocaeli Üniversitesi Adresli: Evet

Özet

Objective: Vascular events are a common complication in patients with polycythemia vera (PV) and essential thrombocythemia (ET). This study aimed to analyze the association between PAI-1 4G/5G and ACE I/D gene polymorphisms, and leukocytosis with thrombosis in patients with PV and ET.