Effect of pentylenetetrazole and sound stimulation induced single and repeated convulsive seizures on the MDA, GSH and NO levels, and SOD activities in rat liver and kidney tissues

DİLLİOĞLUGİL M. Ö., Kir H., Demir C., İLBAY G., ŞAHİN D., DİLLİOĞLUGİL Ö., ...Daha Fazla

BRAIN RESEARCH BULLETIN, cilt.83, sa.6, ss.356-359, 2010 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 83 Sayı: 6
  • Basım Tarihi: 2010
  • Doi Numarası: 10.1016/j.brainresbull.2010.09.007
  • Dergi Adı: BRAIN RESEARCH BULLETIN
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.356-359
  • Anahtar Kelimeler: Epilepsy, Seizure, Pentylenetetrazole, MDA, NO, SOD, GSH, Liver, Kidney, INDUCED EPILEPTIC SEIZURE, THIOL REDOX STATE, OXIDATIVE STRESS, NITRIC-OXIDE, LIPID-PEROXIDATION, WAG/RIJ RATS, BRAIN, MICE, MODEL, ACID
  • Kocaeli Üniversitesi Adresli: Evet

Özet

Objectives The aim of our study was to evaluate the activity of superoxide dismutase (SOD) and the levels of glutathione (GSH) malondialdehyde (MDA) and nitric oxide (NO) in liver and kidney tissues in a rat model of convulsive seizure induced by single and repeated doses of pentylenetetrazole (PTZ) and sound stimulation with key ringing