Effect of sirolimus in the prevention of adhesions around intraabdominal prosthetic graft

Kanko W., Ozbudak E., Ozerdem A., Aksoy A., Kilic M., Berki K. T.

WORLD JOURNAL OF SURGERY, vol.30, pp.1648-1652, 2006 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 30 Issue: 9
  • Publication Date: 2006
  • Doi Number: 10.1007/s00268-005-0750-1
  • Title of Journal : WORLD JOURNAL OF SURGERY
  • Page Numbers: pp.1648-1652


Background: Adhesions due to the reactions caused by the grafts used in primary vascular operations can lead to various problems when a secondary operation is necessary. These problems include bleeding, injuries to neighboring organs, and complications occurring due to a prolonged operation. We investigated the effects of sirolimus, which has antiproliferative features, on vascular adhesions.