Smoking and schizophrenia: Where is the biological connection?

Uneri O., Tural U., Memik N.

TURK PSIKIYATRI DERGISI, cilt.17, sa.1, ss.55-64, 2006 (SSCI) identifier identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 17 Sayı: 1
  • Basım Tarihi: 2006
  • Dergi Adı: TURK PSIKIYATRI DERGISI
  • Derginin Tarandığı İndeksler: Social Sciences Citation Index (SSCI), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.55-64
  • Anahtar Kelimeler: smoking, nicotine, schizophrenia, dopamine, nicotinic acetylcholine receptor, BRAIN NICOTINIC RECEPTORS, MONOAMINE-OXIDASE B, ALZHEIMERS-DISEASE, CIGARETTE-SMOKING, PARKINSONS-DISEASE, COGNITIVE PERFORMANCE, PSYCHIATRIC-DISORDERS, CARDIOVASCULAR HEALTH, NUCLEUS-ACCUMBENS, MAJOR DEPRESSION
  • Kocaeli Üniversitesi Adresli: Evet

Özet

Objective: Patients with psychiatric disorders have a higher incidence of smoking than the general population. In particular, the rate of smoking among patients with schizophrenia has been found to be between two and three times in the general population in western countries. This paper reviews the biological factors that might be contributing to the high rate of smoking among patients with schizophrenia and examines the interaction between nicotine and neurobiological disturbances observed in schizophrenia.