Research Information System
14th İnternational Congress of Academic Research, Ankara, Turkey, 14 - 15 October 2024, vol.1, pp.146-155, (Full Text)
In this study, the morphological features of testicular tumors and their association with specific prognostic parameters were evaluated. Testicular tumors diagnosed between January 2008 and January 2023 were examined. Parameters such as patient age, tumor size and location, histological type, lymphovascular invasion (LVI), epididymal invasion, hilar adipose tissue invasion, spermatic cord invasion, and necrosis were recorded. 89 patients were evaluated in the study. 91.1% of the tumors were germ cell tumors (GCTs). The distribution of GCTs was as follows: 42 (46.7%) seminomas, 29 (32.2%) mixed GCTs, 8 (8.9%) embryonal carcinomas, 1 (1.1%) choriocarcinoma, 1 (1.1%) yolk sac tumor and 1 (1.1%) spermatocytic tumor. 40 (44.4%) patients had LVI, 11 (12.2%) patients had epididymal invasion, 4 (4.4%) patients had spermatic cord invasion, 2 (2.2%) patients had hilar fat tissue invasion, 25 (27.7%) patients had tunica albuginea invasion, 38 (42.2%) patients had necrosis. In testicular tumors, it has been observed that as tumor size increases, the rates of lymphovascular invasion (LVI), epididymal invasion, hilar tissue invasion, tunica albuginea invasion, and necrosis also rises. Tumors with a diameter of ≥3 cm have higher rates of tunica albuginea invasion and lymphovascular invasion (LVI). Keywords: Germ cell tumor, Seminoma, Testis, Testicular Cancer
Bu araştırmada testis tümörlerinin morfolojik özellikleri ve bu özelliklerin belirli prognostik parametrelerle ilişkisinin değerlendirilmesi amaçlanmıştır. Ocak 2008- Ocak 2023 tarihleri arasında tanı konulan testis tümörleri incelendi. Hasta yaşı, tümör çapı ve yerleşimi, histolojik tip, lenfovasküler invazyon (LVİ), epididim invazyonu, hiler yağ doku invazyonu, spermatik kord invazyonu, nekroz gibi parametreler kaydedildi. Çalışmada 89 hasta değerlendirildi. Tümörlerin % 91,1’i germ hücreli tümör (GHT)’du. GHT’lerin dağılımı ise 42 (%46,7) seminom, 29 (%32,2) mikst GHT, 8 (%8,9) embriyonel karsinom, 1 (%1,1) koryokarsinom, 1 (%1,1) yolk sak tümör, 1 (%1,1) spermatositik tümördü. 40 (%44,4) hastada LVI, 11 (%12,2) hastada epididim invazyonu, 4 (%4,4) hastada spermatik kord invazyonu, 2 (%2,2) hastada hiler yağ doku invazyonu, 25 (%27,7) hastada tunika albuginea invazyonu, 38 ( %42,2) hastada nekroz tespit edildi. Testis tümörlerinde tümör boyutu arttıkça LVİ, epididim invazyonu, hiler yağ doku invazyonu, tunika albuginea invazyonu ve nekroz görülme oranının arttığı gözlendi. Tümör çapı ≥3 cm tümörler daha yüksek tunica albuginea invazyonu ve LVI oranına sahiptir.