EFFECTS OF A PORPHYRAZINE DERIVATIVE ON SOME DEVELOPMENTAL CHARACTERISTICS OF DROSOPHILA MELANOGASTER


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KARATAŞ A. , Ertan F., ŞAKİ N. , BAŞPINAR E., Sevim A. M. , Gul A.

ACTA BIOLOGICA HUNGARICA, cilt.62, ss.426-440, 2011 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 62 Konu: 4
  • Basım Tarihi: 2011
  • Doi Numarası: 10.1556/abiol.62.2011.4.8
  • Dergi Adı: ACTA BIOLOGICA HUNGARICA
  • Sayfa Sayıları: ss.426-440

Özet

In this study, the effects of a porphyrazine derivative, [octakis (2-trimethylammoniumethyl thio) porphy-razinatocobalt] octaiodide (CoPzq), were explored on the developmental characteristics, sex ratio and egg fertility of Drosophila melanogaster. CoPzq was preferred in the study due to its probability to be used as a chemotherapeutic agent in medicine. As a result of the application of CoPzq, a phenotypic abnormality was revealed within the individuals of F-1 and F-2 generation of Drosophila. Although individuals of F-2 generation did not directly come into contact with the chemical, the rate of abnormality is high. An increase was observed within both generations in terms of the egg fertility. Besides, a deviation emerged in the sex-ratio in some concentrations.