EFFECTS OF A PORPHYRAZINE DERIVATIVE ON SOME DEVELOPMENTAL CHARACTERISTICS OF DROSOPHILA MELANOGASTER

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KARATAŞ A., Ertan F., ŞAKİ N., BAŞPINAR E., Sevim A. M., Gul A.

ACTA BIOLOGICA HUNGARICA, vol.62, no.4, pp.426-440, 2011 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 62 Issue: 4
  • Publication Date: 2011
  • Doi Number: 10.1556/abiol.62.2011.4.8
  • Journal Name: ACTA BIOLOGICA HUNGARICA
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.426-440
  • Kocaeli University Affiliated: Yes

Abstract

In this study, the effects of a porphyrazine derivative, [octakis (2-trimethylammoniumethyl thio) porphy-razinatocobalt] octaiodide (CoPzq), were explored on the developmental characteristics, sex ratio and egg fertility of Drosophila melanogaster. CoPzq was preferred in the study due to its probability to be used as a chemotherapeutic agent in medicine. As a result of the application of CoPzq, a phenotypic abnormality was revealed within the individuals of F-1 and F-2 generation of Drosophila. Although individuals of F-2 generation did not directly come into contact with the chemical, the rate of abnormality is high. An increase was observed within both generations in terms of the egg fertility. Besides, a deviation emerged in the sex-ratio in some concentrations.