The reaction of 3,4-epoxy-5-hydroxyandrostanes with hydrobromic acid


Baldwin D., Hanson J., UYANIK C.

JOURNAL OF CHEMICAL RESEARCH-S, no.3, pp.200-204, 1999 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: Issue: 3
  • Publication Date: 1999
  • Doi Number: 10.1039/a808315k
  • Title of Journal : JOURNAL OF CHEMICAL RESEARCH-S
  • Page Numbers: pp.200-204

Abstract

The formation of aromatic and ketonic products from the treatment of 17 beta-acetoxy-3 alpha,4 alpha-epoxy-5 alpha-hydroxyandrostane and its 3 beta,4 beta-epoxy-5 beta-hydroxy isomer with hydrobromic acid in glacial acetic acid is discussed in the context of the diaxial and diequatorial opening of the epoxide.