Internet of Things (IoT) based biomedical applications are deployed in biomedical systems such as healthcare/telecare, diagnosis, prevention, treatment, monitoring. Wireless body area networks (WBANs) and radio frequency identification (RFID) systems, also called as enabling technologies, are key components of the IoT concept. In this study, a new IoT-based healthcare framework associated with WBANs and RFID technologies is built for hospital information systems. The designed framework has been modeled and simulated using Riverbed Modeler software. The results show that QoS criteria for data rate and latency specified by ISO/IEEE 11073 standard are satisfied by using the proposed energy-aware system. It is also demonstrated that some case studies considered in hospital information systems can be easily realized by the proposed framework by forming a time-saving simulation environment.