TI-201 imaging in the diagnostic work-up of squamous cell carcinoma metastasis of unknown primary origin

Demir H., Berk F., Erdincler O., Isgoren S., Aktolun C.

CLINICAL NUCLEAR MEDICINE, vol.27, no.5, pp.385-386, 2002 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Editorial Material
  • Volume: 27 Issue: 5
  • Publication Date: 2002
  • Doi Number: 10.1097/00003072-200205000-00024
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.385-386
  • Kocaeli University Affiliated: Yes


A 79-year-old man had undergone surgical implantation of a femoral prosthesis necessitated by metastasis of squamous cell carcinoma of unknown primary origin, which had caused a pathologic fracture in the left femur neck. One year after surgery, a mass was discovered in the patient's left hip that was accompanied by swelling and pain in the entire left leg. A computed tomographic (CT) scan of the pelvis and a bone scan were followed by TI-201 imaging, which excluded the possibility of local infection. Biopsy of the palpable mass in the left hip confirmed local metastatic invasion of squamous cell carcinoma of unknown primary origin in the left femur neck. The patient died 2 months after this diagnosis.