OVERLAPPING POL/S GENE ANALYSIS IN CHRONIC HEPATITIS B PATIENTS WITH COEXISTING HBSAG AND ANTI-HBs


Suntur B. M., SAYAN M., Kaya H., Unal N.

ACTA MEDICA MEDITERRANEA, vol.35, no.6, pp.3113-3119, 2019 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 35 Issue: 6
  • Publication Date: 2019
  • Doi Number: 10.19193/0393-6384_2019_6_489
  • Journal Name: ACTA MEDICA MEDITERRANEA
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.3113-3119
  • Kocaeli University Affiliated: Yes

Abstract

Introduction: Simultaneous HBsAg and anti-HBs positivity can be seen in patients with chronic hepatitis B (CHB) infection. The paradoxical phenomenon of ongoing viral replication despite the presence of neutralizing antibodies makes simultaneous HBsAg and anti-HBs positivity one of the most interesting atypical serological profiles. The aim of this study was to investigate the relationship between the coexistence of HBsAg and anti-HBs and S gene mutations in study and control groups with CHB infection.