OVERLAPPING POL/S GENE ANALYSIS IN CHRONIC HEPATITIS B PATIENTS WITH COEXISTING HBSAG AND ANTI-HBs

Suntur B. M., SAYAN M., Kaya H., Unal N.

ACTA MEDICA MEDITERRANEA, cilt.35, sa.6, ss.3113-3119, 2019 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 35 Sayı: 6
  • Basım Tarihi: 2019
  • Doi Numarası: 10.19193/0393-6384_2019_6_489
  • Dergi Adı: ACTA MEDICA MEDITERRANEA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.3113-3119
  • Kocaeli Üniversitesi Adresli: Evet

Özet

Introduction: Simultaneous HBsAg and anti-HBs positivity can be seen in patients with chronic hepatitis B (CHB) infection. The paradoxical phenomenon of ongoing viral replication despite the presence of neutralizing antibodies makes simultaneous HBsAg and anti-HBs positivity one of the most interesting atypical serological profiles. The aim of this study was to investigate the relationship between the coexistence of HBsAg and anti-HBs and S gene mutations in study and control groups with CHB infection.