Factors affecting facial selectivity in the hydroboration of steroidal Delta(5)-alkenes

Arantes S., Hanson J., Liman M., Manickavasagar R., UYANIK C.

JOURNAL OF CHEMICAL RESEARCH-S, sa.9, ss.530-531, 1998 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: Sayı: 9
  • Basım Tarihi: 1998
  • Doi Numarası: 10.1039/a803403f
  • Dergi Adı: JOURNAL OF CHEMICAL RESEARCH-S
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.530-531
  • Kocaeli Üniversitesi Adresli: Evet

Özet

A comparison between the alpha- and beta-facial selectivity observed in the hydroboration of some androst-5-enes and beta-norandrost-5-enes does not parallel the difference between the calculated force field energies for alpha- and beta-cyclobutane models suggesting that the facial selectivity is not determined by the four-centre transition state but by the relative ease of formation of the initial pi-complex between the alkene and the borane.