Cross-phenotype analysis of Immunochip data identifies KDM4C as a relevant locus for the development of systemic vasculitis


Ortiz-Fernandez L., David Carmona F., Lopez-Mejias R., Francisca Gonzalez-Escribano M., Lyons P. A. , Morgan A. W. , et al.

ANNALS OF THE RHEUMATIC DISEASES, cilt.77, ss.589-595, 2018 (SCI İndekslerine Giren Dergi)

  • Cilt numarası: 77 Konu: 4
  • Basım Tarihi: 2018
  • Doi Numarası: 10.1136/annrheumdis-2017-212372
  • Dergi Adı: ANNALS OF THE RHEUMATIC DISEASES
  • Sayfa Sayısı: ss.589-595

Özet

Objetive Systemic vasculitides represent a heterogeneous group of rare complex diseases of the blood vessels with a poorly understood aetiology. To investigate the shared genetic component underlying their predisposition, we performed the first cross-phenotype meta-analysis of genetic data from different clinically distinct patterns of vasculitis.