Cross-phenotype analysis of Immunochip data identifies KDM4C as a relevant locus for the development of systemic vasculitis

Ortiz-Fernandez, Lourdes; David Carmona, Francisco; Lopez-Mejias, Raquel; Francisca Gonzalez-Escribano, Maria; Lyons, Paul; Morgan, Ann; Sawalha, Amr; Smith, Kenneth; Gonzalez-Gay, Miguel; Martin, AYTEN

doi:10.1136/annrheumdis-2017-212372

Cross-phenotype analysis of Immunochip data identifies KDM4C as a relevant locus for the development of systemic vasculitis

Ortiz-Fernandez L., David Carmona F., Lopez-Mejias R., Francisca Gonzalez-Escribano M., Lyons P. A., Morgan A. W., ...More

ANNALS OF THE RHEUMATIC DISEASES, vol.77, no.4, pp.589-595, 2018 (SCI-Expanded)

Publication Type: Article / Article
Volume: 77 Issue: 4
Publication Date: 2018
Doi Number: 10.1136/annrheumdis-2017-212372
Journal Name: ANNALS OF THE RHEUMATIC DISEASES
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.589-595
Kocaeli University Affiliated: Yes

Abstract

Objetive Systemic vasculitides represent a heterogeneous group of rare complex diseases of the blood vessels with a poorly understood aetiology. To investigate the shared genetic component underlying their predisposition, we performed the first cross-phenotype meta-analysis of genetic data from different clinically distinct patterns of vasculitis.