Cross-phenotype analysis of Immunochip data identifies KDM4C as a relevant locus for the development of systemic vasculitis


Ortiz-Fernandez L., David Carmona F., Lopez-Mejias R., Francisca Gonzalez-Escribano M., Lyons P. A. , Morgan A. W. , ...More

ANNALS OF THE RHEUMATIC DISEASES, vol.77, no.4, pp.589-595, 2018 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 77 Issue: 4
  • Publication Date: 2018
  • Doi Number: 10.1136/annrheumdis-2017-212372
  • Title of Journal : ANNALS OF THE RHEUMATIC DISEASES
  • Page Numbers: pp.589-595

Abstract

Objetive Systemic vasculitides represent a heterogeneous group of rare complex diseases of the blood vessels with a poorly understood aetiology. To investigate the shared genetic component underlying their predisposition, we performed the first cross-phenotype meta-analysis of genetic data from different clinically distinct patterns of vasculitis.