Cross-phenotype analysis of Immunochip data identifies KDM4C as a relevant locus for the development of systemic vasculitis

Ortiz-Fernandez L., David Carmona F., Lopez-Mejias R., Francisca Gonzalez-Escribano M., Lyons P. A., Morgan A. W., ...Daha Fazla

ANNALS OF THE RHEUMATIC DISEASES, cilt.77, sa.4, ss.589-595, 2018 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 77 Sayı: 4
  • Basım Tarihi: 2018
  • Doi Numarası: 10.1136/annrheumdis-2017-212372
  • Dergi Adı: ANNALS OF THE RHEUMATIC DISEASES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.589-595
  • Kocaeli Üniversitesi Adresli: Evet

Özet

Objetive Systemic vasculitides represent a heterogeneous group of rare complex diseases of the blood vessels with a poorly understood aetiology. To investigate the shared genetic component underlying their predisposition, we performed the first cross-phenotype meta-analysis of genetic data from different clinically distinct patterns of vasculitis.