Endoscopic Transsphenoidal Approach for Acromegaly with Remission Rates in 401 Patients: 2010 Consensus Criteria


ANIK İ. , ÇABUK B. , Gokbel A., SELEK A. , Cetinarslan B. , ANIK Y. , ...More

WORLD NEUROSURGERY, vol.108, pp.278-290, 2017 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 108
  • Publication Date: 2017
  • Doi Number: 10.1016/j.wneu.2017.08.182
  • Title of Journal : WORLD NEUROSURGERY
  • Page Numbers: pp.278-290
  • Keywords: Adenoma, Cavernous sinus, Endoscope, Growth hormone, Transsphenoidal approach, SECRETING PITUITARY-ADENOMAS, GROWTH-HORMONE LEVELS, LONG-TERM REMISSION, SURGICAL-TREATMENT, CAVERNOUS SINUS, SURGERY, MANAGEMENT, CURE, PREDICTORS, PSEUDOCAPSULE

Abstract

BACKGROUND: Transsphenoidal surgery is the first-choice treatment for acromegaly. Postoperative remission is an important predictor of outcome. Various factors have been described as markers of remission: preoperative mean growth hormone (GH) and insulin-like growth factor-1 levels, cavernous sinus invasion, tumor size, extrapseudocapsular resection, and experience of the surgeon.