The effect of isradipine on maximal electroshock seizures in mice
GENERAL PHARMACOLOGY-THE VASCULAR SYSTEM, cilt.31, ss.133-135, 1998 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 31
- Basım Tarihi: 1998
- Doi Numarası: 10.1016/s0306-3623(97)00390-x
- Dergi Adı: GENERAL PHARMACOLOGY-THE VASCULAR SYSTEM
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.133-135
- Anahtar Kelimeler: isradipine, maximal electroshock seizure, mice, CALCIUM ENTRY BLOCKERS, EXCITATORY AMINO-ACIDS, ADD-ON THERAPY, SPINAL-CORD, RAT-BRAIN, RECEPTORS, EPILEPSY, CHANNELS, NEURONS, SYSTEM
- Kocaeli Üniversitesi Adresli: Evet
Özet
1. The aim of this study was to investigate the possible anticonvulsant effect of a dihydropyridine calcium antagonist, isradipine, which easily crosses the blood-brain barrier displaying high affinity and specificity for the brain L-type voltage-sensitive calcium channel, on maximal electroshock seizures in mice.