Identification of miR-139-5p as a saliva biomarker for tongue squamous cell carcinoma: a pilot study


Duz M. B., Karatas O. F., Guzel E., Turgut N. F., YILMAZ M. Y., Creighton C. J., ...Daha Fazla

CELLULAR ONCOLOGY, cilt.39, sa.2, ss.187-193, 2016 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 39 Sayı: 2
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1007/s13402-015-0259-z
  • Dergi Adı: CELLULAR ONCOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.187-193
  • Anahtar Kelimeler: Tongue squamous cell carcinoma, miRNA, Biomarker, Saliva, Microarray, TUMOR-MARKERS, MICRORNA EXPRESSION, WHOLE SALIVA, CANCER, SERUM, RNA, DIAGNOSIS, PROFILE, PLASMA
  • Kocaeli Üniversitesi Adresli: Hayır

Özet

Of all human oral carcinomas, 41 % are localized to the tongue. Despite considerable improvements in both diagnosis and treatment, tongue squamous cell carcinoma (TSCC) has remained one of the most lethal types of cancer. Here, we aimed at identifying a salivary microRNA (miRNA) expression signature specific for TSCC patients.