Role of Mesenchymal Stem Cells Transfected With Vascular Endothelial Growth Factor in Maintaining Renal Structure and Function in Rats with Unilateral Ureteral Obstruction


Ozbek E., Adaş G., Otunctemur A., Duruksu G. , Koç B., Polat E. C. , ...More

EXPERIMENTAL AND CLINICAL TRANSPLANTATION, vol.13, pp.262-272, 2015 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 13
  • Publication Date: 2015
  • Doi Number: 10.6002/ect.2014.0080
  • Title of Journal : EXPERIMENTAL AND CLINICAL TRANSPLANTATION
  • Page Numbers: pp.262-272

Abstract

Objectives: Mesenchymal stem cells hold promise for renal disease treatment. Vascular endothelial growth factor may heal tubule-interstitial fibrosis in unilateral ureteral obstruction by inhibiting epithelial-mesenchymal transition. We investigated the protective effect of vascular endothelial growth factor in transfected mesenchymal stem cells in unilateral ureteral obstruction-induced renal injury in rats.