Titanium alloys are the most advantageous metals for the medical and aerospace industry because of their light weight and excellent corrosion resistance. Several techniques were investigated to achieve reliable welds with optimal distortion for the fabrication components used in industry. Laser welding is the most important joining technique because of its precision, rapid processing. For pulse mode Nd:YAG laser; pulse shape, energy, duration, repetition rate and peak power are the most important parameters effects the weld quality. And also the combinations of these parameters are very important for pulsed laser seam-welding. In this study, an experimental work has been done to determine the pulsed laser seam-welding parameters for 3mm thick titanium alloys using the Lumonics JK760TR Nd:YAG pulsed laser.