Effect of resveratrol and metformin on ovarian reserve and ultrastructure in PCOS: an experimental study

Rencber S. H. , Ozbek S. K. , Eraldemir C. , Sezer Z., Kum T., Ceylan S. , ...Daha Fazla

JOURNAL OF OVARIAN RESEARCH, cilt.11, 2018 (SCI İndekslerine Giren Dergi) identifier identifier identifier


Background: PCOS is a reproductive hormonal abnormality and a metabolic disorder. It is frequently associated with insulin resistance, hyperandrogenism, chronic inflammation, and oxidative stress. We aim to investigate the potential therapeutic effects of combined therapy of resveratrol and metformin on polycystic ovaries via SIRT1 and AMPK activation.