Protective effect of hydrogen sulfide on renal injury in the experimental unilateral ureteral obstruction

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Dursun M., Otunctemur A., Ozbek E., Sahin S., Besiroglu H., ÖZSOY Ö. D., ...More

INTERNATIONAL BRAZ J UROL, vol.41, no.6, pp.1185-1193, 2015 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 41 Issue: 6
  • Publication Date: 2015
  • Doi Number: 10.1590/s1677-5538.ibju.2014.0090
  • Journal Name: INTERNATIONAL BRAZ J UROL
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1185-1193
  • Keywords: Ureteral Obstruction, Hydrogen Sulfide, Nephrogenic Fibrosing Dermopathy, Oxidative Stress, OXIDATIVE STRESS, KAPPA-B, RATS, DAMAGE, EXPRESSION, NEPHROTOXICITY, ANTIOXIDANT, FIBROSIS
  • Kocaeli University Affiliated: Yes

Abstract

Introduction/Objective: Ureteral obstruction is a common pathology and causes kidney fibrosis and dysfunction at late period. In this present study, we investigated the antifibrotic and antiinflammatory effects of hydrogen sulfide on kidney damage after unilateral ureteral obstruction (UUO) in rats.