Predictive value of lymphocyte-to-monocyte ratio in patients with contrast-induced nephropathy after percutaneous coronary intervention for acute coronary syndrome
JOURNAL OF TRANSLATIONAL INTERNAL MEDICINE, cilt.9, sa.2, ss.123-130, 2021 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 9 Sayı: 2
- Basım Tarihi: 2021
- Doi Numarası: 10.2478/jtim-2021-0024
- Dergi Adı: JOURNAL OF TRANSLATIONAL INTERNAL MEDICINE
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.123-130
- Anahtar Kelimeler: lymphocyte-to-monocyte ratio, acute coronary syndrome, contrast-induced nephropathy, percutaneous coronary intervention, ACUTE KIDNEY INJURY, ELEVATION MYOCARDIAL-INFARCTION, TERM OUTCOMES, RISK-FACTORS, ASSOCIATION, NEUTROPHIL, PLATELET, DYSFUNCTION, UNDERWENT, SEVERITY
- Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
- Kocaeli Üniversitesi Adresli: Evet
Özet
Background and Objectives: Lymphocyte-to-monocyte ratio (LMR) has emerged as a new indirect marker of inflammation, which is associated with adverse outcomes in cardiovascular diseases. The aim of this study was to evaluate whether admission LMR is associated with contrast-induced nephropathy (CIN) in patients who underwent percutaneous coronary intervention for acute coronary syndrome (ACS). Methods: A total of 873 patients were assessed. LMR was calculated via dividing lymphocyte count by monocyte count. Results: LMR was significantly lower in the with-CIN group. ROC analysis showed that the LMR ratios <2.52 predicted CIN development with sensitivity of 66.3% and specificity of 55.8%. Multivariate analysis showed that eGFR, admission glucose, and LMR were independent predictors of CIN in patients with ACS. Conclusion: LMR is an easily accessible marker and could be used as a predictor of CIN in patients with ACS undergoing percutaneous coronary intervention.