The stereochemistry of an elimination reaction accompanying the hydroboration of a steroidal allylic alcohol

Hanson J., Liman M., UYANIK C.

JOURNAL OF CHEMICAL RESEARCH-S, no.3, pp.126-127, 1998 (SCI-Expanded, Scopus) identifier identifier

  • Publication Type: Article / Article
  • Volume: Issue: 3
  • Publication Date: 1998
  • Doi Number: 10.1039/a708181b
  • Journal Name: JOURNAL OF CHEMICAL RESEARCH-S
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.126-127
  • Kocaeli University Affiliated: Yes

Abstract

Deuterium labelling studies have shown that the facile elimination of the 5 beta-hydroxy group observed in the course of hydroboration of a 5 beta-hydroxyandrost-3-ene may involve a trans diaxial borane-borinate elimination coupled with a syn transfer of hydrogen from the borinate.