Akademik Veri Yönetim Sistemi
International Marmara Sciences Congress (Imascon Autumn) 2022, Kocaeli, Türkiye, 9 - 10 Aralık 2022, ss.67, (Özet Bildiri)
Nanotechnological applications are constantly being developed and the release into the environment is increasing. It is extremely crucial to investigate nano-bio-interactions in order to obtain a clearer picture of the overall effects of nanoparticles on living organisms. The importance of understanding these interactions in insects, which constitute a large part of vitality, emerges. It is proposed that insects are environmentally exposed to nanoparticles through various routes such as skin, respiration or digestion. Therefore, it was aimed to determine the oxidative effect of aluminium oxide (Al2O3) nanoparticles, which are the most commonly produced in the nanomaterial industry, on the model insect Galleria mellonella. Al2O3 nanoparticles were administered to G. mellonella larvae with diets prepared at various concentrations. At the end of chronic treatment, oxidative parameters were analysed by haemolymph samples taken from control and experimental groups. Lipid peroxidation and advanced oxidation protein products were measured in larval haemolymph. In addition, the effect of nanoparticles on the reducing power of iron, which expresses antioxidant capacity, was determined. As a result of the data obtained, it was observed that Al2O3 nanoparticles increased lipid peroxidation and protein oxidation. It was determined that especially high concentrations of Al2O3 nanoparticles caused toxicity on G. mellonella by ingestion. Antioxidant capacity levels did not show any change. These nanoparticle-induced changes in the haemolymph content of G. mellonella larvae reveal that nanotechnological and toxicological studies on different species may provide a basis for nanotechnological and toxicological studies.