Blood and tissue nitric oxide and malondialdehyde are prognostic indicators of localized prostate cancer

DİLLİOĞLUGİL M. Ö., Mekik H., Muezzinoglu B., Ozkan T. A., Demir C. G., DİLLİOĞLUGİL Ö.

INTERNATIONAL UROLOGY AND NEPHROLOGY, vol.44, no.6, pp.1691-1696, 2012 (SCI-Expanded, Scopus) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 44 Issue: 6
  • Publication Date: 2012
  • Doi Number: 10.1007/s11255-012-0221-1
  • Journal Name: INTERNATIONAL UROLOGY AND NEPHROLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1691-1696
  • Keywords: Prostate cancer, Malondialdehyde, Nitric oxide, PSA, OXIDATIVE DNA-DAMAGE, LIPID-PEROXIDATION, EXPRESSION, SYNTHASE, CARCINOMA, DISEASE
  • Kocaeli University Affiliated: Yes

Abstract

Objectives Our objective was to examine blood and tissue levels of nitric oxide (NO) and malondialdehyde (MDA), and their correlations with well-known prognostic indicators [total prostate-specific antigen (tPSA), % free/total PSA (% f/t PSA), pathological stage (pT), and Gleason sum] in patients who had radical retropubic prostatectomy (RRP) for localized prostate cancer (PCa) without metastasis.