Blood and tissue nitric oxide and malondialdehyde are prognostic indicators of localized prostate cancer


DİLLİOĞLUGİL M. Ö., Mekik H., Muezzinoglu B., Ozkan T. A., Demir C. G., DİLLİOĞLUGİL Ö.

INTERNATIONAL UROLOGY AND NEPHROLOGY, cilt.44, sa.6, ss.1691-1696, 2012 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 44 Sayı: 6
  • Basım Tarihi: 2012
  • Doi Numarası: 10.1007/s11255-012-0221-1
  • Dergi Adı: INTERNATIONAL UROLOGY AND NEPHROLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1691-1696
  • Anahtar Kelimeler: Prostate cancer, Malondialdehyde, Nitric oxide, PSA, OXIDATIVE DNA-DAMAGE, LIPID-PEROXIDATION, EXPRESSION, SYNTHASE, CARCINOMA, DISEASE
  • Kocaeli Üniversitesi Adresli: Evet

Özet

Objectives Our objective was to examine blood and tissue levels of nitric oxide (NO) and malondialdehyde (MDA), and their correlations with well-known prognostic indicators [total prostate-specific antigen (tPSA), % free/total PSA (% f/t PSA), pathological stage (pT), and Gleason sum] in patients who had radical retropubic prostatectomy (RRP) for localized prostate cancer (PCa) without metastasis.