The effects of somatostatin on the microperfusion of the pancreas during acute necrotizing pancreatitis in rats


Piri M., Alhan E., Kucuktulu U., Ercin C., Deger O., Yucel K., ...Daha Fazla

HEPATO-GASTROENTEROLOGY, cilt.49, ss.833-837, 2002 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 49 Konu: 45
  • Basım Tarihi: 2002
  • Dergi Adı: HEPATO-GASTROENTEROLOGY
  • Sayfa Sayıları: ss.833-837

Özet

Background/Aims: Autodigestion and impairment of microcirculation of the pancreas play an important role in the pathogenesis of acute pancreatitis. Somatostatin with the reducing effect on the hepatosplachnic blood flow decreases exocrine pancreatic secretion. Microcirculatory changes are central to the pathogenesis of acute pancreatitis. However, little is known about the effects of somatostatin on the pancreatic tissue oxygen pressure and acinar cell injury during acute pancreatitis.