Research Information System
Retina-Vitreus, vol.34, no.3, pp.240-246, 2025 (Scopus)
Purpose: Brucellosis is a zoonotic infection that can manifest in various forms, including neurobrucellosis. This case study aims to highlight a rare ocular involvement of brucellosis in a young, previously healthy male, specifically focusing on a unique presentation of severe vision loss, retinal vasculitis, and Roth’s spot. Methods: Single-center, case report. Results: This case study reports on a 25-year-old male patient who was previously healthy and presented with severe vision loss, optic disc edema, extensive vasculitis, and Roth spot in a single eye due to ocular involvement associated with brucellosis. The diagnosis of brucellosis was confirmed through laboratory tests, including the tube agglutination test, which had a positive titer of 1/160. The patient was administered systemic antibiotics, including doxycycline, rifampin, and ceftriaxone, along with steroids. The treatment resulted in an improvement in the patient’s vision and the resolution of ocular lesions within three months. Conclusion: Roth spots are primarily associated with subacute infective endocarditis. Our case is unique as Brucella-induced Roth’s spot without endocarditis has not been previously reported.