In this study, 69 patients with malignity suspected laryngeal lesion were examined by direct microlaryngoscopy for primary diagnosis. Each lesion was biopsied first. Subsequently touch smear cytology was obtained from the biopsies. In all cases, cytologic slides (one per biopsy) were screened and compared to corresponding biopsies. Lesions were categorized as: Benign, laryngeal intraepitelyal neoplasia (LIN) and malignant.