Histopathologic and molecular comparative analyses of intravesical Aurora kinase-A inhibitor Alisertib with bacillus Calmette-Gu,rin on precancerous lesions of bladder in a rat model


Teke K. , Yılmaz H. , Uslubaş A. K. , Akpınar G. , Kasap M. , Mutlu O. , et al.

INTERNATIONAL UROLOGY AND NEPHROLOGY, cilt.50, ss.1417-1425, 2018 (SCI İndekslerine Giren Dergi)

  • Cilt numarası: 50
  • Basım Tarihi: 2018
  • Doi Numarası: 10.1007/s11255-018-1914-x
  • Dergi Adı: INTERNATIONAL UROLOGY AND NEPHROLOGY
  • Sayfa Sayısı: ss.1417-1425

Özet

Recent studies have shown that Aurora-A expression is associated with bladder cancer initiation and progression. In this study, the effects of intravesical Aurora-A inhibitor Alisertib (ALS) and bacillus Calmette-Gu,rin (BCG) were compared on bladder carcinogenesis.