Akademik Veri Yönetim Sistemi
EANS 2025, Vienna, Avusturya, 5 - 09 Ekim 2025, ss.198, (Özet Bildiri)
Pituitary tumors account for approximately 15% of primary intracranial neoplasms, with many cases diagnosed incidentally. Transsphenoidal surgery, particularly the endoscopic approach, remains theprimary treatment for pituitary tumors despite the advancement of non-surgical treatments. A rare yet significant complication following this surgery is sphenoid sinus osteitis, an infectious condition characterized by inflammation of the bone. This study aims to report the incidence and risk factors of sphenoid sinus osteitis following endoscopic transsphenoidal pituitary tumor resection. Methods A retrospective analysis was conducted on 1,908 patients who underwent endoscopic transsphenoidal surgery for sellar base tumors between September 2021 and November 2024. CT imaging were used to evaluate bony involvement in the sphenoid sinus, with severity categorized based on bone thickness: mild (<3 mm), moderate (4–5 mm), and severe (>5 mm). The presence of osteitis was assessed based on radiographic evidence of neo-osteogenesis. Results Of the 1,908 patients, 12 (0.0063%) were diagnosed with sphenoid sinus osteitis during routine postoperative follow-ups. The cohort consisted of 10 women and 2 men with a mean age of 38 years. The most common presenting symptoms were cacosmia, nasal blockage, and headache. 83% of patients had isolated sphenoid sinus involvement, while there mainder had additional ethmoid sinus involvement. The most significant risk factor identified was a history of endoscopic transsphenoidal surgery, commonly performed for pituitary adenoma resection. Conclusions Endoscopic transsphenoidal surgery remains the primary treatment for pituitary tumors due to its minimally invasive nature and shorter recovery times. However, postoperative complications such as sphenoid sinus osteitis may arise. The pathophysiology of osteitis following pituitary tumor resection remains poorly understood, and although surgical intervention is recommended for severe cases, the role of long-term antibiotic therapy remains unclear. This study, although limited by a small sample size and single-institution data, is the first to evaluate sphenoid sinus osteitis in this context, providing valuable insight into a rare postoperative complication