Late-onset Anticonvulsant Hypersensitivity Syndrome Mimicking Lymphoma

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GEDÜK A., Atesoglu E. B., MEHTAP Ö., DEMİRSOY E. T., CAN B., TARKUN P., ...Daha Fazla

INTERNAL MEDICINE, cilt.54, sa.24, ss.3201-3204, 2015 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 54 Sayı: 24
  • Basım Tarihi: 2015
  • Doi Numarası: 10.2169/internalmedicine.54.5111
  • Dergi Adı: INTERNAL MEDICINE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.3201-3204
  • Anahtar Kelimeler: anticonvulsant hypersensitivity syndrome, lymphadenopathy, pseudolymphoma, SYSTEMIC SYMPTOMS, EOSINOPHILIA, RASH, VIRUS, DRUGS
  • Kocaeli Üniversitesi Adresli: Evet

Özet

Anticonvulsant hypersensitivity syndrome is a fatal, idiosyncratic drug reaction that is caused by aromatic antiepileptic drugs. This cutaneous drug reaction is also called pseudolymphoma because of its clinical and histological similarities with malignant lymphoma. The primary clinical findings are fever, skin rashes, enlarged lymph nodes, single or multiple internal organ involvement and hematological abnormalities. Typically, anticonvulsant hypersensitivity syndrome occurs 1-8 weeks after drug administration. We herein present the case of a patient who had been on anticonvulsant therapy for five years and died from late-onset anticonvulsant hypersensitivity syndrome.